Innovative Scientific Research
Innovative Scientific Research
Time: 2026-09-10 08:49:47
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【Title】Blink behaviour, tear film stability and ocular surface interactions in New Zealand Chinese children
【Journal】Cont Lens Anterior Eye
【Authors】Vivienne Zhang; James S Wolffsohn
【Summary】This study characterized ocular surface physiology and examined associations between blink behavior, tear film stability, eyelid morphology, and ocular surface changes in 61 Chinese myopic children aged 7–12 years living in New Zealand. Incomplete blinking was observed in 53% of participants and was more common in children with single or incomplete double eyelids. Children with incomplete blinking had significantly shorter NIBUT than complete blinkers (5.9 vs 8.1 s, p=0.021). Reduced tear film stability was associated with both upper and lower lid wiper epitheliopathy (LWE), with a stronger association for the upper lid. After adjustment for age and sex, NIBUT remained independently associated with upper lid LWE, suggesting interactions among blink dynamics, tear film instability, and lid–ocular surface friction.
【Title】Drug selection for anti-inflammatory therapy of dry eye disease
【Journal】Zhonghua Yan Ke Za Zhi
【Authors】Z G Liu; Y Liu
【Summary】This review examines the role of inflammation in the onset and progression of dry eye disease (DED) and discusses current approaches to anti-inflammatory treatment. It summarizes clinical evidence and experience regarding the evaluation of ocular surface inflammation, selection of anti-inflammatory drugs, combination therapy, perioperative management, and patient education. The review emphasizes that appropriate and precise selection of anti-inflammatory agents is important for improving treatment outcomes in DED. It aims to provide a scientific, standardized, and practical reference for clinical diagnosis and management, particularly as understanding of DED pathogenesis and the clinical use of anti-inflammatory therapies continue to evolve.